Representation of the NeuroNames Ontology in OWL
Douglas Bowden (University of Washington - Seattle), Fahim Imam (Fahim Imam [email@example.com]), Maryann Martone (University of California at San Diego (UCSD))
Development of Test Cases by which to demonstrate utility of the product, such as automated ways to generate human readable hierarchies from the ontology database; mediation of data exchange based on standardized metadata; exploitation of logical inference in responding to specific kinds of query
Identification of Existing Protocols developed for NIFSTD that can be applied to the conversion and outline protocols to incorporate the remaining knowledge base of NN
Use OWL API tools to develop a first draft of the ontology with simple constraints extracted from NN, augmenting more rigorous relations manually or semi-automatically and utilizing OBO-RO for object properties and IAO for annotation properties.
Integrate information on the presence or absence of structures in the four species most studied by neuroscientists: human, macaque, rat and mouse.
Integrate information from NN on brain structures that do not map to the boundaries of classical neuroanatomical structures but whose overlaps can be represented in OWL
The OWL document will be made available from a permanent URL and will be accessible through the INCF portal via the PONS and the NCBO Bioportal.
This work supported by grants from INCF, Office of the Director (ORIP), NIH and USPHS grant RR00166.